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Syphilis and HIV Infection |
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| รหัสดีโอไอ | |
| Creator | Warangkana Munsakul |
| Title | Syphilis and HIV Infection |
| Publisher | Vajira Medical Journal |
| Publication Year | 2559 |
| Journal Title | Vajira Medical Journal |
| Journal Vol. | 60 |
| Journal No. | 2 |
| Page no. | 147 - 158 |
| Keyword | Syphilis, HIV infection |
| ISSN | 0125-1252 |
| Abstract | Syphilis and HIV infection, both are sexually transmitted diseases. After outbreak in 80 years ago, penicillin treatment and aggressive syphilis control public health campaigns led to decrease in syphilis cases. Since HIV/AIDS era, the numbers of syphilis cases were upswing. This article intends to review how to manage syphilis that is re-emerged in cases of HIV co-infection. Syphilis infection was associated with elevated risk of HIV infection. Clinical manifestation is more severe in syphilis and HIV co-infection patients. Diagnosis and treatment among individuals with HIV infection who also have syphilis are usually the same as among individuals without HIV infection who acquire syphilis. Parenteral penicillin is the preferred drug for treating persons in all stages of syphilis. The use of highly active antiretroviral therapy may reduce syphilis serologic failure rates among HIV-infected patients who have syphilis. Antiretroviral therapy decreases neurological complications of syphilis. Persons exposed sexually to syphilis patients should be evaluated clinically and serologically and treated. After treatment, clinical and serologic evaluation should be performed longer than in non HIV-infected patients. Penicillin, ceftriaxone and doxycycline can be used as an efficient treatment, and no significant differences in serological response. |
