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Lidocaine Gel Combined with Ibuprofen Versus Ibuprofen Alone for Pain Relief during an Endometrial Biopsy;A randomized controlled trial |
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| รหัสดีโอไอ | |
| Creator | Kemmanut Tueman |
| Title | 1. Lidocaine Gel Combined with Ibuprofen Versus Ibuprofen Alone for Pain Relief during an Endometrial Biopsy 2. A randomized controlled trial |
| Contributor | Tanyalak Wongleucha |
| Publisher | PIMDEE Co., Ltd. |
| Publication Year | 2569 |
| Journal Title | Thai Journal of Obstetrics and Gynaecology |
| Journal Vol. | 34 |
| Journal No. | 1 |
| Page no. | 30-41 |
| Keyword | endometrial biopsy, lidocaine gel, ibuprofen, pain control |
| URL Website | https://tci-thaijo.org/index.php/tjog/index |
| Website title | www.tci-thaijo.org |
| ISSN | 2673-0871 |
| Abstract | Objectives: To study the effect of 2% lidocaine gel in conjunction with ibuprofen for pain relief during endometrial biopsy.Materials and Methods: Women who met the eligibility criteria were randomly allocated into two groups. The intervention group received 2% lidocaine gel (3 mL), while the control group received the placebo gel (3 mL). Both groups received oral ibuprofen 400 mg 30 minutes before the procedure. The pain score in each step of the procedure, starting from speculum insertion, grasping the cervix, during endometrial biopsy, immediately after the procedure, and 10 minutes after the procedure, was assessed by a 10-cm visual analogue scale. Any adverse effects were also recorded. Results: Eighty-six women, 43 in each group, were recruited during July to December 2024. Baseline characteristics, including age, parity, and menopausal status, were not different in both groups. The mean pain score during endometrial biopsy in the intervention group (3.30 ? 2.09) was significantly lower than in the control group (5.33 ? 2.01) (mean difference -2.03, 95% confidence interval -2.91 to -1.15, p < 0.001). Pain scores at each step of the procedure in the intervention group were lower than in the control group but not statistically different. Adverse effects were not found, and the satisfaction of both patients and physicians was satisfied. Conclusion: The addition of 2% lidocaine gel was effective in reducing pain during endometrial biopsy when compared to ibuprofen alone. |
