|
Cell cytotoxicity evaluation of silver microemulsion for intranasal antibacterial use in acute bacterial rhinosinusitis: A pharmacological study |
|---|---|
| รหัสดีโอไอ | |
| Creator | Prayuth Poowaruttanawiwit |
| Title | Cell cytotoxicity evaluation of silver microemulsion for intranasal antibacterial use in acute bacterial rhinosinusitis: A pharmacological study |
| Contributor | Kwanchai Rattanamanee, Niratcha Chaisomboon, Hathairat Lekatana, Chanida Chantim |
| Publisher | The Pharmacological and Therapeutic Society of Thailand |
| Publication Year | 2566 |
| Journal Title | Journal of Basic and Applied Pharmacology |
| Journal Vol. | 3 |
| Journal No. | 2 |
| Page no. | R26-33 |
| Keyword | cell cytotoxicity, silver microemulsion, acute bacterial rhinosinusitis |
| URL Website | https://li01.tci-thaijo.org/index.php/JBAP |
| Website title | เว็บไซต์คลังข้อมูล |
| ISSN | 2774-0854 (Online) |
| Abstract | Acute bacterial rhinosinusitis is a commonly observed condition marked by inflammation and infection of the sinuses, prompting the exploration of alternative therapeutic approaches, such as the utilization of topical antibacterial agents incorporating silver nanoparticles. However, prior to clinical translation, a comprehensive evaluation of the safety profile is indispensable. This review article places emphasis on diverse safety pharmacological investigations, specifically cell cytotoxicity assays, conducted to assess the potential adverse effects of silver microemulsion on human cells. Additionally, this review highlights other pharmacological methodologies aimed at ensuring safety prior to efficacy testing and subsequent formulation development of an appropriate preparation. |
