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Antibacterial activity of Rosa damascena Extract against Acne- Inducing Bacteria (Cutibacterium acnes) |
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| รหัสดีโอไอ | |
| Creator | kittiphong songsarn |
| Title | Antibacterial activity of Rosa damascena Extract against Acne- Inducing Bacteria (Cutibacterium acnes) |
| Contributor | Thida Chaiwangsri |
| Publisher | Pathumthani University |
| Publication Year | 2568 |
| Journal Title | Pathumthani Health Sciences Journal |
| Journal Vol. | 6 |
| Journal No. | 2 |
| Page no. | 30-44 |
| Keyword | Rosa damascena, Cutibacterium acnes, antibacterialactivity |
| URL Website | https://ph01.tci-thaijo.org/index.php/PTUJST |
| Website title | Pathumthani Health Sciences Journal |
| ISSN | 3088-2516 (Online) |
| Abstract | This study aimed to evaluate the antibacterial activity of crude ethanolic extract from Rosa damascenapetals against Cutibacterium acnes, an anaerobic bacterium that plays a significant role in the pathogenesis of inflammatory acne, a common dermatological condition in the general population. The minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined using the broth macro-dilution method at concentrations of 200, 100, 50, 25, 12.5, 6.25, 3.125, and 1.5625 mg/mL.The crude extract was obtained using 95% ethanol, yielding 6.41% (w/w) of the dried petal weight. The results revealed that the extract exhibited both inhibitory and bactericidal effects against C. acneswith MIC and MBC values of 6.25 mg/mL. In comparison, tetracyclinea commonly used antibiotic in acne treatmentdemonstrated significantly lower MIC and MBC values of 0.9375 ?g/mL, indicating superior antibacterial efficacy. However, prolonged use of antibiotics may contribute to the emergence of resistant bacterial strains. Therefore, R. damascenaextract presents a promising natural alternative for the development of anti-acne skincare products or therapeutic agents. Utilizing plant-derived antimicrobials may help reduce dependency on antibiotics and mitigate the risk of antibiotic resistance, offering long-term benefits to public health. |
