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Application value of time of appearance of Mycoplasma pneumoniae IgM antibodies in rapid diagnosis |
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| รหัสดีโอไอ | |
| Creator | Ling Gao |
| Title | Application value of time of appearance of Mycoplasma pneumoniae IgM antibodies in rapid diagnosis |
| Contributor | Xia Wang, Jingjing Han, Lijiao He |
| Publisher | Maejo University |
| Publication Year | 2569 |
| Journal Title | Maejo International Journal of Science and Technology |
| Journal Vol. | 20 |
| Journal No. | 1 |
| Page no. | 83 |
| Keyword | pediatric Mycoplasma pneumoniae pneumonia, rapid diagnosis, quantitative Mycoplasma pneumoniae IgM, white blood cell, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio |
| Website title | Maejo International Journal of Science and Technology |
| ISSN | 1905-7873 |
| Abstract | This retrospective study examines the optimal timing for Mycoplasma pneumoniae (MP) IgM detection in children with clinical symptoms such as cough and fever, and evaluates the diagnostic value of MP-IgM levels with routine blood tests. Clinical data from 149 children with MP IgM positivity were analysed, focusing on symptom onset times and changes in IgM levels, white blood cell (WBC), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) at varying symptom durations. Coughing appeared as early as 24 hr after infection, with fever following 12 hr later. The median cough duration was 7 days, with 54.4% of children testing IgM positive within this period, while fever was present in 59.1% of cases. IgM, WBC, NLR and PLR levels were significantly higher than those in the control group in children with cough durations of 8-15 days, and prolonged fever (>3 days) correlated with higher IgM and PLR levels. It is concluded that for children with suspected MP infection, quantitative MP-IgM testing combined with routine blood parameters (WBC, NLR, PLR) is recommended for rapid diagnosis, particularly in those with cough persisting >7 days or fever lasting >3 days. |
