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Clinical study of lactulose combined with acupoint catgut embedding on maintenance hemodialysis patients complicated with functional constipation |
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| รหัสดีโอไอ | |
| Creator | Fei Guo |
| Title | Clinical study of lactulose combined with acupoint catgut embedding on maintenance hemodialysis patients complicated with functional constipation |
| Contributor | Lijing Chen |
| Publisher | Maejo University |
| Publication Year | 2566 |
| Journal Title | Maejo International Journal of Science and Technology |
| Journal Vol. | 17 |
| Journal No. | 3 |
| Page no. | 201 |
| Keyword | lactulose, acupoint catgut embedding, maintenance hemodialysis, functional constipation |
| Website title | Maejo International Journal of Science and Technology |
| ISSN | 1905-7873 |
| Abstract | This study explores the clinical effect of lactulose combined with acupoint catgut embedding on maintenance hemodialysis (MHD) patients with functional constipation. Patients with MHD complicated with functional constipation in the blood purification centre of Huzhou Central Hospital were enrolled and randomly divided into a control group and an observation group, with 30 cases in each group. The control group was treated with lactulose oral liquid, and the observation group was treated with lactulose oral liquid + acupoint catgut embedding. The scores of constipation symptoms and the average number of weekly spontaneous complete bowel movement (SCBM) were compared between the two groups before and after treatment. Serum brain-gut peptide-related indicators and indoxyl sulfate indicators were used before and after treatment, and the short-term efficacy of the patients was evaluated. Results showed that after treatment, the scores of stool properties, defecation frequency, difficulty, and defecation time in the observation group were significantly lower than those in the control group (P<0.01). The frequency of SCBM in the observation group was significantly more than that in the control group in 2-4 weeks of treatment (P<0.05). Compared with the control group after treatment, the serum 5-hydroxytryptamine four receptors level in the observation group significantly increased (P<0.01), and the serum somatostatin, vasoactive intestinal peptide, and indoxyl sulfate levels significantly decreased (all P<0.01). The results of the curative effect evaluation showed that the total effective rate of the observation group (90.00%) was significantly higher than that of the control group (63.33%, P<0.05). Thus, lactulose combined with acupoint catgut embedding can achieve a good curative effect in the treatment of functional constipation complicated by MHD, relieve the symptoms of constipation, increase the frequency of SCBM, mediate the level of serum brain-gut peptide-related indicators, and promote the recovery of intestinal-kidney function. Thus, this method can alleviate defecation troubles, thereby improving the quality of life of MHD patients. |
